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Lymphocytes aminergic binding changes in chronic lymphocytic leukaemia |
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| Authors: | J.M. Bidart P. Motte C. Bohuon D. Bellet |
| Affiliation: | Unité de Biologie Clinique et Expérimentale, Institut Gustave-Roussy, 94800, Villejuif, France |
| Abstract: | β-Adrenergic and dopaminergic binding were studied on intact normal human lymphocytes and abnormal lymphocytes from patients with chronic lymphocytic leukaemia (CLL). For both aminergic receptors, a significant difference was found between the two groups. Our results suggest that membrane alterations in the unregulated cellular proliferation may modify several hormone receptors. |
| Keywords: | Chronic lymphocytic leukaemia lymphocytes normal human lymphocytes β-adrenergic receptors dopaminergic receptor |
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