糖尿病性神经病变

糖尿病性神经病变是糖尿病常见的并发症,其病理机制非常复杂,高血糖和微血管病变是其主要的发病机制。以远侧对称性神经病为主要表现,麻木、疼痛、痛觉过敏、肌无力等严重地影响患者的生活质量。目前已经有大量的检查手段来区分特异的神经成分病变,但对其疼痛治疗和评估常被忽略,错过了最佳的治疗时机。联合采用控制血糖、神经营养、改善循环以及合理选择镇痛药物与神经阻滞等措施是治疗和延缓糖尿病性神经病变的最佳策略。

The diabetic neuropathies

The diabetic neuropathies is a well-known complication of diabetes. It's pathogenesis is very complex. Excess glucose and vascular insufficiency is the main reason. The most common and widely recognized form of diabetic nerve injury is distal symmetric neuropathy. Numbness, pain, allodynia and weakness seriously impact on quality of the diabetic patient's life. Many measures of examing and distinguishing the pathological changes had been presented, however, proper diagnosis and therapy may be overlooked at a stage when they are most treatable. Combined glucose control, nerve nutrition drugs, improvement of blood circulation, properly selecting analgesics and nerve blocks are prime strategies for treating and for preventing diabetic neuropathies from progression.