| 细胞黏附分子与肺癌侵袭转移的关系 |
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| 引用本文： | 郑敏娜,陆融,姚智. 细胞黏附分子与肺癌侵袭转移的关系[J]. 国外医学(肿瘤学分册), 2006, 0(7) |
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| 作者姓名： | 郑敏娜 陆融 姚智 |
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| 作者单位： | 天津医科大学免疫教研室(郑敏娜)，深圳康哲药业有限公司(陆融) |
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| 基金项目： | 国家“863”高技术研究发展计划资助项目(2004AA2Z3170和2005AA2Z3D40)，国家“973”基础研究前期资助项目(2003CCA04300) |
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| 摘 要： | 细胞黏附分子(CAM)与肿瘤侵袭转移的关系密切,能够介导肿瘤细胞与细胞外基质、血管内皮细胞、实质器官组织细胞以及肿瘤细胞之间的相互作用。现就近年来细胞黏附分子在肺癌侵袭转移中的作用作一综述。
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| 关 键 词： | 肺肿瘤 细胞黏附分子 肿瘤转移 |
Adhesion molecules and their role in lung cancer Invasion and metastasis |
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| ZHENG Min-na LU Rong. Adhesion molecules and their role in lung cancer Invasion and metastasis[J]. Foreign Medical Sciences (Cancer Section), 2006, 0(7) |
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| Authors: | ZHENG Min-na LU Rong |
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| Affiliation: | ZHENG Min-na LU Rong Department of Immunology,Tianjin Medical University,Tianjin,300070,China |
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| Abstract: | Lung cancer is one of malignant neoplasms which have the fastest growing incidence -and morta lites worldwide.The high mortality of this disease attributes to its local invasion and/or metas- tasis to distant organs.Recent researches suggest that expression level of cell adhesion molecules is close- ly relative to invasion and metastasis of tumor cells.Adhesion molecules mainly mediate the adhesion of tumor cell to extracellular matrix,vascular endothelial cells,histiocytes or other tumor cells,and promote the invasion and metastasis of tumor cells.This is an attempt to summarize the roles of adhesion molecules in lung cancer invasion and metastasis. |
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| Keywords: | Iung neoplasms Cell adhesion molecules Neoplasm metastasis |
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