Interferon-beta 1a and SARS coronavirus replication |
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| Authors: | Hensley Lisa E Fritz Lisa E Jahrling Peter B Karp Christopher L Huggins John W Geisbert Thomas W |
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| Affiliation: | Virology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA. |
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| Abstract: | A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon-beta 1a potently inhibits SARS coronavirus replication in vitro. |
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| Keywords: | SARS interferon coronavirus treatment therapy |
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