| 55例病理证实的慢性肝炎与血清HBV标志物关系的探讨 |
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| 引用本文： | 王麟士,李兵顺.55例病理证实的慢性肝炎与血清HBV标志物关系的探讨[J].河北医科大学学报,1989,10(1):25-28. |
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| 作者姓名： | 王麟士 李兵顺 |
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| 作者单位： | 河北医学院附属三院传染病科，河北医学院附属三院传染病科，河北医学院附属三院传染病科，河北医学院附属三院传染病科，河北医学院附属三院传染病科，河北医学院附属三院传染病科，河北医学院附属三院传染病科病理科，河北医学院附属三院传染病科检验科 |
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| 摘 要： | 本文选用了特异性强、敏感度高的检测方法(SPRIA及ELISA),对经病理证实的55例慢性肝炎全部进行了血清HBV标志物的检测,其中41例并用斑点杂交法检测HBV-DNA,发现它除对乙型肝炎的诊断、病毒复制及临床预后等方面具有重要意义外,作者提出有些问题如对单项抗-HBs阳性、抗-HBs及抗-HBc双项阳性、抗-HBe阳性、PIISA受体及HBV-DNA等应予重视和重新评价。
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| 关 键 词： | 慢性肝炎 血清乙肝病毒标志物 病理诊断 |
RELATIONSHIP BETWEEN LIVER BIOPSY AND SEROLOGIC HBV MARKERS IN CHRONIC VIRAL HEPATITIS (ANALSIS OF 55 CASES) |
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| Wang Linshi Pei Xiu Liu Jinxing Cao Zhichen Li Bingshuen Yin Naining Wei Meixin Liu Yanfang.RELATIONSHIP BETWEEN LIVER BIOPSY AND SEROLOGIC HBV MARKERS IN CHRONIC VIRAL HEPATITIS (ANALSIS OF 55 CASES)[J].Journal of Hebei Medical University,1989,10(1):25-28. |
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| Authors: | Wang Linshi Pei Xiu Liu Jinxing Cao Zhichen Li Bingshuen Yin Naining Wei Meixin Liu Yanfang |
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| Abstract: | In this study, we report 55 cases of viral hepatitis examined with serologic HBV markers (HBVM) by means of SPRIA and ELISA. In 41 cases of them HBV-DNA were detected by spot hybridization. All cases were proved by transcutaneous liver biopsy. There were 34 cases of CPH, 20 CAH, and 1 AVH. There was a significant correlation between the liver biopsy and HBVM in chronic hepatitis. It is very important to decide the diagnosis and prognosis of hepatitis B and the replication of HBV. At the same time, we also found that some problems of HBVM, as anti-HBs(+), anti-HBS/anti-HBC (+), anti-HBe(+), PHSA-receptor and HBV-DNA, should be revisited and evaluated. |
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| Keywords: | chronic viral hepatitis HBV markers (HBVM) liver biopsy pathologic diagnosis |
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