Emergency treatment of renal colic with intravenous Ketoprofen |
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Authors: | M A El-Baz M El-Tayeb Nasser |
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Institution: | (1) Departments of Urology and Nephrology, Ain Shams University, Cairo, Egypt |
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Abstract: | The non-steroidal anti-inflammatory drug (NSAID) Ketoprofen (Profenid) is used as intravenous monotherapy incorporated in
0.9% normal saline solution (100 mg Ketoprofen ampoule +200 ml normal saline) in the treatment of renal colic.
We present our experience in 65 patients complaining of clinically diagnosed renal colic who were treated by intravenous saline-Ketoprofen.
Prospective investigations revaled urinary calculi in 51 patients, oxaluria (crystalluria) in 5, acute colitis in 2, severe
myositis in 2, negative investigations in 3 and radiculitis in 2 patients.
Positive response was observed in 93.8% of patients as far as pain relief is concerned. Pain relief started within 5–7 minutes
after beginning the infusion. Duration of analgesic effect ranged between 4 and 12 hours. Repeating the injection was done
for maintenance of analgesia.
Side effects included drowsiness in 2 patients, palpitation in 1 patient, epigastric pain in 1, muscular cramp in 1 patient.
Ketoprofen, an antiprostaglandin, is a powerful anti-inflammatory and potent analgesic. Intravenous saline-Ketoprofen is a
good emergency treatment for acute episodes of renal colic. |
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