| CD_4~+ CD_(25)~+调节性T细胞与动脉粥样硬化 |
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| 引用本文： | 李安,曹晶茗. CD_4~+ CD_(25)~+调节性T细胞与动脉粥样硬化[J]. 医学综述, 2009, 15(6): 807-810 |
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| 作者姓名： | 李安 曹晶茗 |
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| 作者单位： | 昆明医学院第一附属医院心内科,昆明,650032 |
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| 摘 要： | 动脉粥样硬化是一种慢性炎症性疾病,而且炎性反应的起始与持续都有先天性和获得性免疫应答的参与。CD4+ CD25+调节性T细胞(CD4+ CD25+ Treg)是一个具有独特免疫调节功能的T细胞亚群,能够抑制效应T细胞的活性。过去许多研究已证实,CD4+ CD25+ Treg在动脉粥样硬化中起着重要作用,本文综述了CD4+ CD25+ Treg与动脉粥样硬化的关系。
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| 关 键 词： | 调节性T细胞 辅助性T细胞 动脉粥样硬化 |
CD4+CD25+ Regulatory T Cells and Atherosclerosis |
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| LI An,CAO Jing-ming. CD4+CD25+ Regulatory T Cells and Atherosclerosis[J]. Medical Recapitulate, 2009, 15(6): 807-810 |
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| Authors: | LI An CAO Jing-ming |
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| Affiliation: | LI An, CAO Jing-ming( Internal Medicine of Cardiology,the First Affliliated Hospital of Kanming Medical College ,Kunming 650032, China) |
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| Abstract: | Atherosclerosis is a chronic inflammatory disease of the arterial wall where both innate and adaptive immune responses contribute to disease initiation and progression. Subtypes of T cells, called CD4＋ CD25^＋ Treg,have a unique immune regulatory function, they can counteract effector T cells. A number of studies during the past year have comfirmed an important role of CD4^＋ CD25^＋ Tregs in atherosclerosis. This article reviewed the relationship between CD4^＋ CD25^＋ Treg and atherosclerosis. |
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| Keywords: | CD4^＋ CD25^＋ Treg Adjuvanticity T cell Atherosclerosis |
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