补肾化痰方对多囊卵巢综合征患者高雄激素血症的影响

目的:观察补肾化痰方对多囊卵巢综合征患者高雄激素血症的影响。方法:选取2011年2月—2013年2月本院收治的多囊卵巢综合征高雄激素血症患者98例,随机分为对照组和观察组,每组49例。对照组在自然月经或黄体酮撤退性出血第5天开始服用炔雌醇环丙孕酮片治疗,观察组在对照组治疗的基础上加用补肾化痰方治疗。结果:对照组有效率75.51%,观察组有效率91.84%,观察组优于对照组(P0.05);观察组治疗后黄体生成素(luteinizing hormone,LH)、睾酮(testosterone,T)、睢二醇(eseradiol,E2)水平优于对照组(P0.05);两组治疗后F-G评分和痤疮评分均明显下降,观察组治疗后痤疮评分优于对照组(P0.05)。结论:补肾化痰方治疗多囊卵巢综合征高雄激素血症临床效果显著,能明显改善患者LH、T、E2水平。

The Influence of Kidney-Supplementing and Phlegm-Removing Decoction on Hyperandrogenism of Patients with Polycystic Ovarian Syndrome

Objective:To observe the clinical curative effect of Kidney-Supplementing and Phlegm-Removing Decoction on hyperandrogenism of patients with polycystic ovarian syndrome (PCOS).Methods:Ninety-eight patients with PCOS who were treated in our hospital between February of 2011 and February of 2013 were chosen and randomly divided into the control group and the observation group,with 49 cases in each group.The ones in the control group began to take ethinylestradiol cyproterone on the 5th day after the natural menstrual or progesterone withdrawal bleeding,while the ones in the observation group were added Kidney-Supplementing and Phlegm-Removing Decoction based on the treatment of the control group.Results:The effective rate of the control group was 75.51％,while that of the observation group was 91.84％;The observation group was better than the control group (P ＜0.05).After the treatment,LH,T,and E2 levels of the observation group were all better than those of the control group (P ＜ 0.05).After the treatment,the two groups' F-G score and ache score were significantly decreased,and acne score of the observation group was better than that of the control group (P＜0.05).Conclusion:Kidney-Supplementing and Phlegm-Removing Decoction has a remarkable clinical curative effect on hyperandrogenism of patients with polycystic ovarian syndrome,can obviously improve their LH,T,and E2 levels.