| 颌面部毛细血管瘤中凋亡相关癌基因蛋白的表达 |
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| 引用本文： | 陈光,贺占国,成继民,王琪,王永海.颌面部毛细血管瘤中凋亡相关癌基因蛋白的表达[J].华北国防医药,2002,14(2):79-80,W001. |
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| 作者姓名： | 陈光 贺占国 成继民 王琪 王永海 |
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| 作者单位： | 解放军白求恩国际和平医院，石家庄050082 |
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| 摘 要： | 目的：探讨毛细血管瘤自行消退的影响因素。方法：以正常皮肤为对照，采用免疫组织化学方法检测了14例毛细血管瘤组织中Ki-67、C-fos及Bcl-23种凋相关癌基因蛋白的表达。结果：毛细血管瘤组织中Ki－67及C-Fos表达明显高于对照组（P＜0．05），但未见Bcl-2的阳性表达。结论：提示凋亡相关癌基因蛋白对毛细血管瘤的消退可能具有重要作用。
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| 关 键 词： | 面部肿瘤 肿瘤基因表达调控 癌基因蛋白质类 Ki－67基因 C－fos基因 Bcl－2基因 基因表达 颌面部毛细血管瘤 免疫组织化学 |
| 文章编号： | 1009-0878(2002)02-0079-02 |
Expressions of the oncoproteins correlated with apoptosis in the capillary hemangioma |
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| CHEN Guang,HE Zhan-guo,CHENG Ji-min,et al..Expressions of the oncoproteins correlated with apoptosis in the capillary hemangioma[J].Medical Journal of Beijing Military Region,2002,14(2):79-80,W001. |
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| Authors: | CHEN Guang HE Zhan-guo CHENG Ji-min |
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| Institution: | CHEN Guang,HE Zhan-guo,CHENG Ji-min,et al.
Bethune International Peace Hospital of PLA .Shijiazhuang 050082 .China |
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| Abstract: | Objective To explore the influential factors for spontaneous regression of capillary hemangioma( CH). Methods Compared with those in normal tisuuse. expressions of the three oncoproteins( Ki-67 ,C-fos and Bcl-2) correlated with apopto-sis were observed in the tomor tissues from 14 cases of CH with immunohistochemistry. Results Expressions of Ki-67 and C-fos were increased significantly(P <0. 05 ) in CH tissues.but no Bcl-2 positive expression was noted. Conclusions It suggested that oncoproteins correlated with apoptosis might play an important role in regression of CH. |
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| Keywords: | Facial neoplasms Gene expression regulation neopi aslic Oncogene proteins |
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