Effects of phenobarbitone and starving on the dopamine content of the adrenal glands of rats exposed to carbon disulphide

Summary Two 4 h inhalation exposures of male rats to 2.0 mg/l CS₂ given on consecutive days increased the dopamine (DA) content of the adrenal gland by 100%. In rats treated with phenobarbitone (Phb) or starved before exposure the increase in adrenal DA was significantly higher. The highest DA content in adrenal glands was found in starved phenobarbitone pretreated rats after CS₂ exposure. Starvation and/or phenobarbitone without CS₂ exposure caused no increase in adrenal DA.