High Serum Interleukin-10 and Tumor Necrosis Factor Alpha Levels in Chronic Paracoccidioidomycosis |
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Authors: | M. C. Fornari, A. J. Bava, M. T. Guere o, V. E. Berardi, M. R. Silaf, R. Negroni, R. A. Diez |
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Affiliation: | M. C. Fornari, A. J. Bava, M. T. Guereño, V. E. Berardi, M. R. Silaf, R. Negroni, and R. A. Diez |
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Abstract: | In patients with chronic paracoccidioidomycosis (n = 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean ± standard error of the mean), were higher than in normal controls (n = 8): 186 ± 40 versus 40 ± 7 (P < 0.05), 203 ± 95 versus 20 ± 8 (P = 0.001), and 96.3 ± 78.57 versus 1.19 ± 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls. |
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