| 米托蒽醌脂质体制备工艺的研究 |
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| 引用本文： | 段逸松,张志荣.米托蒽醌脂质体制备工艺的研究[J].华西药学杂志,2001,16(2):91-92. |
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| 作者姓名： | 段逸松 张志荣 |
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| 作者单位： | 四川大学华西药学院, |
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| 摘 要： | 目的：优选米托蒽醌脂质体制备工艺。方法：以用形态、粒径、包封率为指标评价工艺。结果：逆相蒸发法制备的的脂质体粒径小，包封率高。结论：逆相蒸发法可用作米托蒽醌脂质体的制备工艺。
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| 关 键 词： | 米托蒽醌 脂质体 制备工艺 蒽环类抗生素 |
| 文章编号： | 1006-0103(2001)02-0091-02 |
| 修稿时间： | 2000年12月1日 |
STUDY ON THE PREPARATION TECHNIQUES OF MITOXANTRONE LIPOSOMES |
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| DUAN Yi-song,ZHANG Zhi-rong.STUDY ON THE PREPARATION TECHNIQUES OF MITOXANTRONE LIPOSOMES[J].West China Journal of Pharmaceutical Sciences,2001,16(2):91-92. |
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| Authors: | DUAN Yi-song ZHANG Zhi-rong |
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| Abstract: | OBJECTIVE:To present the optimum method of the preparation of mitoxantrone liposomes METHODS:To select the optimum method with morphology,particle size and entrapping efficiency as criterion RESULTS:A sample with small particle size and high entrapping efficiency has been produced with reverse phase evaporation method CONCLUSION:Reverse phase evaporation is the optimum technique |
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| Keywords: | Mitoxantrone Liposomes Preparation |
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