| 铅神经毒性细胞机制的研究进展 |
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| 引用本文： | 刘忠慧,王凤山.铅神经毒性细胞机制的研究进展[J].环境与健康杂志,2007,24(2):122-123. |
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| 作者姓名： | 刘忠慧 王凤山 |
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| 作者单位： | 1. 天津医科大学公共卫生学院,天津,300070
2. 天津市疾病预防控制中心,天津,300011 |
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| 摘 要： | 铅最强的有害作用就是其神经毒性,发育中的大脑对铅的神经毒性作用极其敏感.该文从铅与钙离子的竞争作用、铅对神经递质的影响及其对海马神经元的脂质过氧化损伤作用三个方面综述了近几年来铅神经毒性细胞机制的研究进展.
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| 关 键 词： | 金属 重 铅 神经毒性 神经递质 脂质过氧化作用 |
| 文章编号： | 1001-5914(2007)02-0122-02 |
| 修稿时间： | 2006-10-20 |
The Progress of Study on Cell Mechanism of Lead Neurotoxicity |
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| LIU Zhong-hui,WANG Feng-shan.The Progress of Study on Cell Mechanism of Lead Neurotoxicity[J].Journal of Environment and Health,2007,24(2):122-123. |
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| Authors: | LIU Zhong-hui WANG Feng-shan |
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| Institution: | School of Public Health ,Tianjin Medical University, Tianjin 300070, China |
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| Abstract: | The most severe adverse effect of lead is neurotoxicity. The brain in development is extremely sensitive to lead. The present paper reviewed the research advances in cell mechanisms of lead neurotoxicity achieved in recent years , namely the competition effect with calcium ion, the impact on neurotransmitter, the lipid peroxidation damage on hippocampus neuron. |
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| Keywords: | Metals heavy:Lead Neurotoxicity Neurotransmitter Lipid peroxidation |
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