| 早孕胎盘滋养层细胞的免疫组化研究 |
| |
| 引用本文： | 史志英,张建民,尹克铮,王建华,韩月明,麻晓迁.早孕胎盘滋养层细胞的免疫组化研究[J].东南大学学报(医学版),1996(2). |
| |
| 作者姓名： | 史志英 张建民 尹克铮 王建华 韩月明 麻晓迁 |
| |
| 作者单位： | 南京铁道医学院病理学教研室，南京铁道医学院组织胚胎学教研室 |
| |
| 摘 要： | 目的：研究早孕胎盘绒毛和子宫蜕膜中合体滋养层细胞、细胞滋养层细胞和中间滋养层细胞的免疫组化特征。方法：对２０例妊娠头３个月的刮宫标本进行Ｋｅｒａｆｉｎ、ｈＣＧ、ＨＰＬ、ＰＬＡＰ、ＥＭＡ和Ｐｒｏｌｅｃｔｉｎ等免疫组化染色。结果：角蛋白是各种滋养层细胞最可靠和最敏感的标记物，但其特异性差。合体滋养层细胞的ｈＣＧ和ＰＬＡＰ染色强于中间滋养层细胞，而中间滋养层细胞的ＨＰＬ和ＥＭＡ染色强于合体滋养层细胞。除角蛋白外，细胞滋养层细胞免疫组化染色均阴性。结论；早孕时三种滋养层细胞在免疫组化方面有其共性，也有各自不同的特点。
|
| 关 键 词： | 合体滋养层细胞 细胞滋养层细胞 中间滋养层细胞 胎盘 早期妊娠 |
Immunocytochemical Demonstration of Trophoblasts in the Early Pregnancy |
| |
| Shi Zhiying , Ma Xiaoqian, Zhang Jianmin,Yin Kezheng,Wang Jianhua, Han Yueming.Immunocytochemical Demonstration of Trophoblasts in the Early Pregnancy[J].Journal of Southeast Univ: Medical Sci Ed,1996(2). |
| |
| Authors: | Shi Zhiying Ma Xiaoqian Zhang Jianmin Yin Kezheng Wang Jianhua Han Yueming |
| |
| Abstract: | OBJECTIVES: To study immunocytochemical features of syncytiotrophoblast(ST), cytotrophoblast (CT) and intermediate trophoblast(IT)in the early pregnancy. METHODS: Twenty specimens of the first trimester villi and deciduas were stained with antibodies to cytokeratin, hCG, HPL, PLAP, EMA and Prolactin. RESULTS:Cytokeratin is the most sensitive and reliable marker for all types of trophoblasts though lacking specificity. Furthermore hCG and PLAP stained ST is stronger than IT, HPL and EMA stained iT stronger than ST. In contrast, CT showed negative stain for all immunocytochemical markers used in this study but cytokeratin. CONCLUSIONS: Though three trophoblasts in the early pregnancy share somewhat common feature's each trophoblast is of its own characteristics immunocytochemically. |
| |
| Keywords: | Syncytiotrophoblasts cytotrophoblasts intermediate tropholasts placenta early pegnancy immunocytochemistry |
| 本文献已被 CNKI 等数据库收录！ |
