|
|||||
|
|
| 异基因造血干细胞移植后并发中枢神经系统急性移植物抗宿主病1例并文献复习 | |
| 引用本文： | 陆英,邹勇,刘文达,黄仁魏,林东军.异基因造血干细胞移植后并发中枢神经系统急性移植物抗宿主病1例并文献复习[J].器官移植,2011,2(3):168-171. |
| 作者姓名： | 陆英 邹勇 刘文达 黄仁魏 林东军 |
| 作者单位： | 1. 510630,广州,中山大学附属第三医院,血液科;510630,广州,中山大学附属第三医院输血科 2. 中山大学附属第三医院输血科,广州,510630 3. 中山大学附属第三医院,血液科,广州,510630 |
| 摘 要： | 目的观察急性白血病患者接受异基因造血干细胞移植（allogeneic hemotopoietic stem cell transplantation,allo-HSCT）后并发中枢神经系统急性移植物抗宿主病（aGVHD）的临床特点。方法回顾性分析1例急性髓细胞白血病（acute myeloid leukemia,AML）M5b型患者于allo-HSCT后并发中枢神经系统aGVHD的临床资料。结果患者接受allo-HSCT后40d突发癫,根据头颅磁共振成像（MRI）表现以及相关科室会诊意见,考虑中枢神经系统aGVHD,经大剂量甲泼尼龙冲击治疗后病情好转,1个月后复查头颅MRI示病灶基本消失。结论急性白血病接受allo-HSCT后发生中枢神经系统aGVHD较少见,临床表现缺乏特异性,加强监测排除其他疾病,确诊后及早使用肾上腺皮质激素（激素）,可使患者获得较好的转归。 |
| 关 键 词： | 骨髓移植 移植物抗宿主病 中枢神经系统 急性白血病 磁共振成像 甲泼尼龙 |
Central nervous system acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation:a case report and literature review |
|
| LU Ying,ZOU Yong,LIU Wen-da,HUANG Ren-wei,LIN Dong-jun.Central nervous system acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation:a case report and literature review[J].Ogran Transplantation,2011,2(3):168-171. | |
| Authors: | LU Ying ZOU Yong LIU Wen-da HUANG Ren-wei LIN Dong-jun |
| Institution: | LU Ying,ZOU Yong,LIU Wen-da,HUANG Ren-wei,LIN Dong-jun. Department of hematology,Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,China |
| Abstract: | Objective To observe clinic feature of central nervous system acute graft-versus-host disease(CNS-aGVHD)after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Method Clinical data of a patient with acute myeloid leukemia(AML)(type M5b)were retrospectively analyzed,who developed CNS-aGVHD after allo-HSCT.Results On day 40 after allo-HSCT,the patient presented with epilepsy.Accoding to head magnetic resonance imaging(MRI)and consultation of related department,CNS-aGVHD was considered.The patient'... |
| Keywords: | Bone marrow transplantation Graft-versus-host disease Central nervous system Acute leukemia Magnetic resonance imaging Methylprednisolone |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |