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Efficacy and safety of endoscopic submucosal dissection under general anesthesia
Authors:Kanefumi Yamashita  Hironari Shiwaku  Toshihiro Ohmiya  Hideki Shimaoka  Hiroki Okada  Ryo Nakashima  Richiko Beppu  Daisuke Kato  Takamitsu Sasaki  Seiichiro Hoshino  Satoshi Nimura  Ken Yamaura  Yuichi Yamashita
Abstract:AIM: To evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) under general anesthesia.METHODS: From January 2011 to July 2014, 206 consecutive patients had undergone ESD under general anesthesia for neoplasms of the stomach, esophagus, and colorectum were enrolled in this retrospective study. The efficacy and safety of ESD under general anesthesia were assessed.RESULTS: The en bloc resection rate of esophageal, gastric, and colorectal lesions was 100.0%, 98.3%, and 96.1%, respectively. The complication rate of perforation and bleeding were 0.0% and 0.0% in esophageal ESD, 1.7% and 1.7% in gastric ESD, and 3.9% and 2.0% in colorectal ESD, respectively. No cases of aspiration pneumonia were observed. All complications were managed by conservative treatment, with no surgical intervention required.CONCLUSION: With the cooperation of an anesthesiologist, ESD under general anesthesia appears to be a useful method, decreasing the risk of complications.
Keywords:Complication   Endoscopic submucosal dissection   General anesthesia   Conscious sedation
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