Current and future applications of mass spectrometry to the clinical laboratory |
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Authors: | Strathmann Frederick G Hoofnagle Andrew N |
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Institution: | University of Washington Medical Center, Seattle, WA 98195-7110, USA. |
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Abstract: | Mass spectrometry is an analytic technique with high specificity and a growing presence in laboratory medicine. Various types of mass spectrometers are being used in an increasing number of clinical laboratories around the world, and, as a result, significant improvements in assay performance are occurring rapidly in areas such as toxicology, endocrinology, and biochemical genetics. This review serves as a basic introduction to mass spectrometry, its uses, and associated challenges in the clinical laboratory and ends with a brief discussion of newer methods with the greatest potential for clinical diagnostics. |
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