食管癌患者手术切除前后SA、CEA和SCP检测的临床意义

目的　探讨食管癌患者手术切除前后血清 SA、CEA、SCP水平的变化。方法　应用放免法测定 4 3例食管癌患者血清 CEA含量 ,化学法测定 SA和 SCP含量 ,并以 35名正常健康人作对照。结果　食管癌患者在手术切除前血清 SA、CEA、SCP水平非常显著地高于正常人组 (P<0 .0 1) ,手术切除后 6个月转移者血清 SA、CEA、SCP水平持续异常 ,未转移者血清 SA、CEA、SCP在正常水平。结论　血清 SA、CEA、SCP含量测定的变化与食管癌患者的病情和预后密切相关 ,有一定的临床应用价值

Clinical significance of detection of SA,CEA and SCP levels in patients with esophagial cancer before and after operation

Objective To analyze the levels of serum SA,CEA and SCP in patients with esophague cancer before and after operation.Methods Serum CEA was detected by RIA while SA and SCP was detected biochemically and compared with those in 35 normal controls.Results Before operation serum SA,CEA and SCP levels were much higher than those in normal controls( P <0.01).Six months after operation SA,CEA and SCP levels were continously abnormal in patients who developed matastasis.SA,CEA and SCP levels returned to normal in patients without matastasis.Conclusion The changes of serum SA,CEA,SCP levels were closely related to the disease condition and prognosis of esophagial cancer.