Secretion of the gastrokinetic agent cisapride in human milk |
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Authors: | G. J. Hofmeyr E. W. W. Sonnendecker |
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Affiliation: | (1) Department of Obstetrics and Gynaecology, Johannesburg Hospital and University of the Witwatersrand, Johannesburg, South Africa |
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Abstract: | Summary Ten puerperal women were treated with the gastrokinetic agent Cisapride 20 mg 8-h by oral tablets. Breast milk levels of Cisapride had reached a steady state by treatment day 3. Day 4 breast milk levels were 6.2±1.3 and serum levels 137±8.1 ng/ml (mean±SEM). The breastfeeding infant of a woman on the above treatment would ingest an amount of Cisapride 600–800 times lower than the usual therapeutic dose. |
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Keywords: | cisapride breast milk secretion |
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