支原体肺炎患儿血、尿胱抑素C检测的临床研究

目的探讨支原体肺炎患儿急性期、恢复期血、尿胱抑素c（CysC）水平及其临床价值。方法支原体肺炎患儿36例，正常对照组120例，分别检测支原体肺炎患儿急性期、恢复期的血、尿胱抑素c、α1-微球蛋白、微量白蛋白、肌酐等指标，并对结果进行统计分析。结果与对照组相比，支原体肺炎患儿急性期血、尿Cysc含量差异均有统计学意义（P〈0．01），而恢复期差异无统计学意义（P〉0．05）；支原体肺炎患儿急性期与恢复期比较，差异有统计学意义（P〈0．05）。结论支原体肺炎患儿急性期肾功能有程度不等的损害，但肾功能损伤是可恢复的；血、尿CysC测定对支原体肺炎患儿早期肾功能损害的诊断具有重要的临床价值。

Clinical Study of Serum and Urine Cystatin C in Children with Mycoplasma Pneumonia

Objective To explore the levers of serum and urine cystatin C （ Cys C） in the acute and recovery phase of infants with mycoplasma pneumonia. Methods The serum and urine cystatin C, α1-microglobutin（ α1-MG）, microalbumin（ MA）, creatinine and other indicators were detected and analyzed in 120 healthy children（ control group） and 36 infants with mycoplasma pneumonia （ observation group）. Results The level of serum and urine Cys C in patients at acute phase was significantly different form the control group and patients at recovery phase（P 〈 0.01 ,P 〈 0.05 ）. There was no obvious difference between the control and recovery phase（P 〉 0.05 ）. Conclusion The injured renal functions in infants with mycoplasma pneumonia at acute phase were recoverable. The detection of serum and urine Cys C levels is helpful for the clinical diagnosis of the early renal function impairment infants with mycoplasma pneumonia.