| 泮托拉唑钠与奥美拉唑钠在氯化钠注射液中的稳定性考察 |
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| 引用本文： | 金瓯,裘蛟恒,张昀,王新月,胡秋丽.泮托拉唑钠与奥美拉唑钠在氯化钠注射液中的稳定性考察[J].中国药师,2007,10(4):355-357. |
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| 作者姓名： | 金瓯 裘蛟恒 张昀 王新月 胡秋丽 |
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| 作者单位： | 1. 浙江省药品检验所,浙江杭州,310004
2. 杭州中美华东制药有限公司 |
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| 摘 要： | 目的:考察注射用泮托拉唑钠和注射用奥美拉唑钠与氯化钠注射液配伍稳定性。方法:用HPLC法考察配伍前后泮托拉唑钠与奥美拉唑钠的含量变化,并观察配伍液的外观及pH变化。结果:注射用泮托拉唑钠和注射用奥美拉唑钠与0.9%氯化钠注射液配伍后8 h内含量、pH及溶液外观均无明显变化。结论:注射用泮托拉唑钠和注射用奥美拉唑钠与氯化钠注射液配伍后在8 h内均稳定。
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| 关 键 词： | 泮托拉唑钠 奥美拉唑钠 配伍稳定性 |
| 文章编号： | 1008-049X(2007)04-0355-03 |
| 修稿时间： | 2006-10-10 |
Study on Compatibility of Pantoprazole Sodium for Injection and Omeprazole Sodium for Injection with Sodium Chloride Injection |
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| Jin Ou,Qiu Jiaoheng,Zhang Yun,Wang Xinyue,Hu Qiuli.Study on Compatibility of Pantoprazole Sodium for Injection and Omeprazole Sodium for Injection with Sodium Chloride Injection[J].China Pharmacist,2007,10(4):355-357. |
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| Authors: | Jin Ou Qiu Jiaoheng Zhang Yun Wang Xinyue Hu Qiuli |
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| Institution: | 1. Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd, Hangzhou 310004, China;2. Zhejiallg Institute for Drug Control |
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| Abstract: | Objective:To Study the compatibility of pantoprazole sodium for injection and omeprasole sodium for injection with So- dium Chloride,Injection.Method:The change in content was determined by HPLC,and the change in appearance and pH was inspec- ted.Result:No obvious changes were noted in terms of contents,pH and appearances.Conclusion:The compatibility admixture of pantoprazole sodium for injection and omeprazole sodium for injection was stability with 0.9% NS within 8 hours. |
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| Keywords: | Pantoprazole sodium Omeprazole sodium Compatibility Stability |
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