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甲基睾丸素与甲酸棉酚合剂对大鼠睾丸的影响
引用本文:张汇泉,施国琳,姜恩亭,杨立忠. 甲基睾丸素与甲酸棉酚合剂对大鼠睾丸的影响[J]. 山东大学学报(医学版), 1986, 0(1)
作者姓名:张汇泉  施国琳  姜恩亭  杨立忠
作者单位:山东医科大学组织学与胚胎学教研室,山东医科大学组织学与胚胎学教研室,山东医科大学组织学与胚胎学教研室,山东医科大学组织学与胚胎学教研室
摘    要:大白鼠每日按每公斤3毫克服甲基睾丸素与15毫克甲酸棉酚合剂10次后,睾丸曲细精管生精上皮遭受损伤,正常精子形成发生障碍,从而产生抗生育效能。通过实验表明应用合剂与分别用药相比,可缩短用药时间,产生节制生育的作用,停药后40天恢复生殖能力。

关 键 词:甲基睾丸素  棉酚  睾丸  精子发生阻滞剂  大鼠

EFFECT OF THE MIXTURE OF METHYL TESTICULINE AND GOSSYPOL FORMATE ON TESTIS OF RATTUS NORVEGICUS VAR ALBUS
Zhang Huiquan. EFFECT OF THE MIXTURE OF METHYL TESTICULINE AND GOSSYPOL FORMATE ON TESTIS OF RATTUS NORVEGICUS VAR ALBUS[J]. Journal of Shandong University:Health Sciences, 1986, 0(1)
Authors:Zhang Huiquan
Abstract:After feeding the rattus norvegicus var, albus with a mixture of methyl testiculine and gossypol formate (3 mg/kg and 15mg/kg respectively) once a day for 10 days,the spermatogenic epithelia of seminiferous tubules were damaged and the dysfunction of spermatogenesis occured. It results in loss of fertility The experiments revealed that the duration for administration of mixture was less than that the two compartments of the mixture given separately. The ablity of reproduction will be restored after stopping giving the medicine of 40 days duration.
Keywords:Methyltesticuline  Gossypol  Testis  Spermatogenesis blocking agents  Rats
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