| 表皮生长因子受体抑制剂及其突变在肺癌治疗中的研究进展 |
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| 引用本文： | 雷琳,万毅新. 表皮生长因子受体抑制剂及其突变在肺癌治疗中的研究进展[J]. 国际呼吸杂志, 2009, 29(12). DOI: 10.3760/cma.j.issn.1673-436X.2009.012.010 |
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| 作者姓名： | 雷琳 万毅新 |
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| 作者单位： | 兰州大学第二医院呼吸科,730000;兰州大学第二医院呼吸科,730000 |
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| 摘 要： | 表皮生长因子受体及其抑制剂是肺癌分子靶向治疗的研究热点,表皮生长因子受体抑制剂已广泛运用于非小细胞肺癌治疗,近年发现表皮生长因子受体突变与其抑制剂的临床疗效关系密切.现就表皮生长因子受体抑制剂及其突变在肺癌治疗中的研究进展作一综述.
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| 关 键 词： | 表皮生长因子受体 基因突变 肺癌 |
Research progress on inhibitors of epidermal growth factor receptor and its mutations in lung cancer treatment |
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| LEI Lin,WAN Yi-xin. Research progress on inhibitors of epidermal growth factor receptor and its mutations in lung cancer treatment[J]. International Journal of Respiration, 2009, 29(12). DOI: 10.3760/cma.j.issn.1673-436X.2009.012.010 |
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| Authors: | LEI Lin WAN Yi-xin |
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| Abstract: | Epidermal growth factor receptor inhibitors are the research focus in the molecular targeted therapy of lung cancer. Epidermal growth factor receptor inhibitors have been widely used for the treatment of non-small cell lung cancer. In recent years, it has been found that epidermal growth factor receptor mutation and its inhibitors are closely related to the clinical efficacy. This article reviews the research progress of epidermal growth factor receptor inhibitors and its mutation in the therapy of lung cancer. |
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| Keywords: | Epidermal growth factor receptor Gene mutation Lung cancer |
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