扁桃体癌近距离插植后装放射治疗疗效分析

目的:分析常规外照射 插植近距离后装放射治疗扁桃体癌的疗效。方法:回顾分析我科1992年1月至2005年12月收治的经病检证实的扁桃体癌39例,采用常规外照射 插植近距离后装放射治疗组(观察组)23例,采用常规外照射治疗组(对照组)16例,比较两组局部控制率和生存率。结果:观察组3、5年局控率分别为86.9%和86.6%,对照组为75.0%和62.5%;观察组3、5年生存率分别为73.9%和52.2%,对照组为68.8%和37.5%。5年生存率分别为:观察组Ⅰ Ⅱ期为77.7%,对照组71.4%。观察组Ⅲ Ⅳ期为35.7%,对照组为22.2%,均无显著性差异(P>0.05)。结论:扁桃体癌患者行外照射 插植近距离后装放射治疗对提高疗效有一定增益,值得进一步深入研究。

Efficacy of brachytherapy by implantation for patients with tonsillar carcinoma

Objective:To evaluate the role of conventional external beam radiation combined with interstitial implantation for tonsillar carcinoma. Methods: From January 1992 to December 2005, cases with tonsillar carcinoma proven pathologyically, were divided into two groups, 23 cases in observed group received conventional external beam radiation combined implantation, and 16 cases of control group received external beam radiation. Local control rates and survival rates were analyzed. Results: The 3-year and 5-year local control rates in observed group were 86.9% and 86.6% respectively; and the 3-year and 5-year local control rates in control group were 75.0% and 62.5% respectively. The 3-year and 5-year survival rates in observed group were 73.9% and 52.2% respectively; the 3-year and 5-year survival rates in control group were 68.8% and 37.5% respectively. The 5-year survival rates were : 77.7% in observed group and 71.4% in control group of I~II stages respectively, 35.7% in observed group and 22.2% in control group of III~IV stages respectively. There were no significant difference with (P>0.05). Conclusion: Conventional external beam radiation combined with implantation can improve the outcme for tonsillar carcinoma.