益气养阴活血汤加灌肠治疗早期糖肾病疗效观察

目的:观察益气养阴活血汤口服加中药灌肠综合治疗早期糖尿病肾病的临床疗效。方法:80例患者随机分为两组,对照组采用单纯西药治疗,治疗组加用益气养阴活血汤口服和中药高位保留灌肠治疗,疗程均为3个月;观察治疗前后症状及实验室相关指标的变化。结果:治疗组总有效率为90.0%,对照组总有效率为62.5%(P<0.05);治疗组24h尿白蛋白排泄率、血糖、血肌酐、血脂等指标的改善均优于对照组(P<0.05,P<0.01)。结论:益气养阴活血汤口服加中药灌肠综合治疗早期糖尿病肾病疗效明显优于单纯西药治疗,而且能更好地改善患者临床症状。

Clinical Study on Oral Use of Yiqi Yangyin Huoxue Decoction and Herbal Enema in Treating Incipient Diabetic Nephropathy

Objective:To observe the curative clinical effect of Yiqi Yangyin Huoxue Decoction(YYHD)and enema of herbal decoction for incipient diabetic nephropathy(DN).Method:80 patients with Incipient DN were divided randomly into 2 groups with 40 cases in each.The control group were treated with western medicine alone.Besides,the treatment group were treated by oral use of YYHD and retention enema of herbal decoction.The course of treatment was three months.Changes of symptoms and related laboratory parameters were observed before and after treatment.Results:The total effective rate was 90.0% in treatment group and 62.5% in control group(P<0.05).The urinary albumin excretion rate,blood sugar,Scr and blood lipid improved better in treatment group than in control group(P<0.05,P<0.01).Conclusion:The curative effect of YYHD and enema of herbal decoction is better than that of Western Medicine alone in treating Incipient DN,and also can alleviate symptoms.