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Fusion and Matrix Protein Gene Sequence Analysis of Paramyxoviruses of Type 1(PMV-1) Isolated from Pigeons in Slovenia
Authors:Darja?Barli?-Maganja  author-information"  >  author-information__contact u-icon-before"  >  mailto:darja.barlic@vf.uni-lj.si"   title="  darja.barlic@vf.uni-lj.si"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Uro??Krape?,Sara?Manko?,Ivan?Toplak,Olga?Zorman?Rojs
Affiliation:(1) Veterinary Faculty, University of Ljubljana, Gerbičeva 60, SI-1115 Ljubljana, Slovenia
Abstract:Paramyxoviruses of type 1 (PMV-l) isolated from pigeons were genetically analyzed. A part of the fusion and the matrix protein genes were amplified and sequenced, Typical amino acid sequences associated with virulence were determined at the fusion protein cleavage site in all PMV-1 isolates. All Slovene pigeon PMV-1 strains share high amino acid sequence similarity with other pigeon strains. In the phylogenetic tree, they are clustered together with pigeon PMV-1 isolates with moderate pathogenicity. Phylogenetic analysis obtained from the fusion and the matrix protein gene alignments showed the same branching order. Viruses circulating among pigeons were found to form quite unique lineage of virulent NDV strains.
Keywords:fusion protein gene  matrix protein gene  Newcastle disease virus  pararmyxovirus type 1  phylogenetic analysis  pigeon
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