| 不同水质致突变性分析 |
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| 引用本文： | 闫鹏,于梅,郑剑,徐景野.不同水质致突变性分析[J].中国公共卫生,2005,21(4):415-416. |
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| 作者姓名： | 闫鹏 于梅 郑剑 徐景野 |
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| 作者单位： | 浙江省宁波市疾病预防控制中心,315010 |
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| 基金项目： | 宁波市科委资助项目 (2 0 0 30 60 ) |
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| 摘 要： | 目的 探讨N市水质的致突变性。方法 应用XAD- 2大孔树脂吸附浓集水中有机物的技术 ,结合Ames试验、微核试验、小鼠精子畸形试验 ,研究N市主要水厂水源水、滤池出水、氯化消毒自来水中非挥发性有机物(NOCs)的致突变性。结果 氯化消毒自来水微核率和精子畸形率显著高于阴性对照组 (P <0. 0 5 ) ,氯化消毒自来水5L/皿剂量下 ,TA98 S9MR =4. 92 ,TA98+S9MR =2 . 6 9。结论 氯化消毒自来水有一定程度致突变性 ,水源水、滤池出水未检出致突变性。
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| 关 键 词： | 水 氯化消毒 致突变性 |
| 文章编号： | 1001-0580(2005)04-0415-02 |
| 修稿时间： | 2004年7月13日 |
Analysis on genotoxicity of different water |
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| YAN Peng,YU Mei,ZHENG Jian,et al..Analysis on genotoxicity of different water[J].Chinese Journal of Public Health,2005,21(4):415-416. |
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| Authors: | YAN Peng YU Mei ZHENG Jian |
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| Institution: | YAN Peng,YU Mei,ZHENG Jian,et al.Ningbo Municipal Center for Disease Control and Prevention |
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| Abstract: | Objective To study the mutagenicity of the water in N city.Methods XAD-2 resin was used to extract the organic atter in water.Ames test,the micronucleus assay and the sperm morphologic test were used to analyze the utagenicity of the nonvolatile organic copounds(NOCs)in water,for the main waterworks'source water,the clarified filtration water and the chlouinated tap water in N city.Results The chlouinated tap water micronucleus rate and seed deformity rate were significantly higher than those in normal group(P<0.05).When the chlouinated tap water dosage was 5L/plate,TA98-S9 MR=4.92,TA98+S9 MR=2.69.Conclusion Mutagenicity was determined by the chlorinated tap water in some degree,but mutagenicity was not found in the source water and the clarifying fillration water. |
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| Keywords: | water chlorination utagenicity |
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