The Italian MacNew heart disease health-related quality of life questionnaire: a validation study |
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Authors: | Email author" target="_blank">Francesco?FattirolliEmail author Niccolò?Marchionni Stefan?H?fer Pantaleo?Giannuzzi Elisabetta?Angelino Paolo?Fioretti Daniela?Miani Neil?Oldridge |
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Institution: | 1.Department of Experimental and Clinical Medicine,University of Florence and Azienda Ospedaliero Universitaria Careggi,Florence,Italy;2.Department of Medical Psychology,Innsbruck Medical University,Innsbruck,Austria;3.Salvatore Maugeri Foundation,IRCCS, Scientific Institutes of Torino and Veruno,Veruno,Italy;4.Azienda Ospedaliero Universitaria S. Maria della Misericordia and IRCAB Foundation,Udine,Italy;5.College of Health Sciences,University of Wisconsin-Milwaukee,Wisconsin,USA |
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Abstract: | Patient-centered treatment outcomes such as health-related quality of life are recommended in clinical care and research studies. Health-related quality of life questionnaires need to be validated in the language of the target population. The reliability and validity of the Italian version of the MacNew Questionnaire was determined in patients with angina, myocardial infarction, or ischemic heart failure. Sociodemographic and clinical data were collected on 298 patients angina, n = 88; MI, n = 106; heart failure, n = 104; mean age, 64.8 (±10.6) years] at three centers in Italy. MacNew mean scores were higher (p < 0.001) in patients with myocardial infarction than in patients with either angina or heart failure with no floor and minimal ceiling effects. The three-factor structure of the original MacNew form was largely confirmed explaining 54.6 % of the total variance. The Italian MacNew version demonstrates high internal consistency reliability (Cronbach’s α ≥ 0.86), confirms the convergent validity hypotheses with strong correlations on six of eight comparisons (r ≥ 0.86), partially confirms discriminative validity with the SF-36 health transition item, and fully confirms discriminative validity with the Hospital Anxiety and Depression Scale. The Italian version of the MacNew Questionnaire demonstrates satisfactory psychometric properties, and is reliable and valid in Italian-speaking patients with angina, MI, or heart failure. Responsiveness could not be tested due to the cross-sectional design of the parent study, and needs to be investigated in an intervention study. |
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