| ACTH对组织浸液活性的反馈作用 |
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| 引用本文： | 邹光楣,何善述,王巽义,梁之彦.ACTH对组织浸液活性的反馈作用[J].华中科技大学学报(医学版),1985(2). |
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| 作者姓名： | 邹光楣 何善述 王巽义 梁之彦 |
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| 作者单位： | 武汉医学院基础医学生化教研室
(邹光楣，何善述，王巽义)，武汉医学院基础医学生化教研室(梁之彦) |
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| 摘 要： | 按不同实验条件制备五组供样动物组织浸液,用放免法测定其受试组血浆皮质酮含量,观察各供样组组织浸液活性。结果提示:①组织浸液活性于注射后半小时达最高峰,至少可维持2小时;②无论在正常条件下或在付肾切除条件下,注射ACTH均可抑制组织浸液活性。推测组织浸液活性因子可能是一种天然存在的生理性物质。
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| 关 键 词： | 组织浸液 促肾上腺皮质激素 皮质酮 副肾切除 放射兔疫测定 |
The Feedback Effect of ACTH on Tissue Extract Activity |
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| Zuo Guangmei,Huo Shanshu,Wang Xienyi,Liang Zhiyan.The Feedback Effect of ACTH on Tissue Extract Activity[J].Journal of Huazhong University of Science and Technology(Health Sciences),1985(2). |
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| Authors: | Zuo Guangmei Huo Shanshu Wang Xienyi Liang Zhiyan |
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| Institution: | Zuo Guangmei,Huo Shanshu,Wang Xienyi,Liang ZhiyanDepartment of Biochemistry,Faculty of Basis Medical Sciences,Wuhan Medical College,Wuhan |
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| Abstract: | Under different experimental conditions male rats regarded as donors are divided into 5 groups,Level of recipient plasm corticosterone of rats determined by RIA is used as an index for assay of tissue extracts activity from donors.The result shows (I) tissue extract activity reached the highest at 30 minutes after injection and last for 2 hours at least (2),it was also observed that ACTH has anegative feedback effect on tissue extract activity either in physiological or in adrenalectomized donors perhaps the factor found in tissue extract might be a kind of physiological material similar to tissue CRF. |
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| Keywords: | Tissue extract ACTH corticosterone adrenalectomy RIA |
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