| 冠状动脉中冷晶体与含血停搏液灌注比较 |
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| 引用本文： | 镡朝晖,朱洪生,富皓白,葛云霞,冯缘.冠状动脉中冷晶体与含血停搏液灌注比较[J].上海交通大学学报(医学版),2001,21(2). |
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| 作者姓名： | 镡朝晖 朱洪生 富皓白 葛云霞 冯缘 |
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| 作者单位： | 上海第二医科大学仁济医院胸外科, |
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| 摘 要： | 目的比较冷晶体停搏液和含血停搏液心肌保护效果。方法应用冷晶体或含血停搏液灌注施行冠状动脉搭桥术35例。冷晶体组采用间断灌注；含血停搏液组灵活交替采用温血、冷血停搏液。结果含血停搏液组与冷晶体停搏液组术前心功能及血清CK-MB值、冠状动脉搭桥支数、体外循环时间无差异，但含血停搏液组主动脉阻断时间显著延长(P＜0.01)。术后血清CK-MB值、自动复跳率无显著差异。结论含血停搏液心肌保护效果不逊于冷晶体停搏液；主动脉阻断时间对心肌保护有更重要影响。
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| 关 键 词： | 心停搏液 心肌保护 体外循环 冠状动脉搭桥术 |
Comparison of Efficacy of Myocardial Protection Between Cold Crystalloid and Blood Cardioplegia |
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| Abstract: | Objective The aim of this study was to compare the efficacy of cold crystalloid cardioplegia with integrated blood cardioplegia for evaluating the adequacy of myocardial protection. Methods Thirty - five patients undergoing coronary artery bypass grafting were randomly allocated to receive intermittent cold crystalloid or blood cardioplegia. Results Preoperative heart function (NYHA), serum CK-MB, number of coronary artery bypass grafts, total bypass time were similar in both groups. However, aortic cross-clamping time in the blood cardioplegia group was significantly longer than in the cold crystalloid cardioplegia group (P＜0.01). Postoperative serum CK-MB was similar in both groups. Conclusion Blood cardioplegia is at least not worse than cold crystalloid cardioplegia. Shortening the aortic cross-clamping time is more important for myocardial protection. |
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