影响新生儿心脏传导阻滞预后的相关因素分析

目的 分析影响新生儿心脏传导阻滞预后的相关因素,为临床合理治疗提供理论依据.方法 回顾性分析21例危重新生儿临床资料,根据预后分为预后不良和预后良好,对各种影响因素与预后的关系进行分析,单因素分析采用Fisher确切概率法,多因素分析采用Logistic回归法.结果 预后不良12例,预后良好9例.单因素分析表明,体重≤1.25 kg、胎龄≤28周、肾功能不全、高钾血症>12 h与预后有关(P均<0.05).Logistic回归分析筛选出肾功能不全是预后的独立影响因素.结论 肾功能不全是影响危重新生儿心脏传导阻滞预后的重要因素,治疗上应加强肾功能的维护和支持.

Analysis of risk factors for prognosis in neonatal cardiac conduction block

Objective To analyze the risk factors for the prognosis in neonatal cardiac conduction block,so as to provide theoretic basis for rational therapy.Methods Clinical data of 21 critical newborns with cardiac conduction block were retrospectively analyzed.According to the prognosis,the infants were divided into good and bad prognosis group.Potential risk factors of prognosis for cardiac conduction block were studied by univariate analysis (Fisher's exact test) and Logistic stepwise regression analysis.Results There were 12 newborns with good prognosis and 9 with bad prognosis.Univariate analysis revealed that body weight ≤1.25kg,gestational age ≤28 weeks,renal dysfunction,hyperkalemia more than 12 hours were associated with bad outcome (P<0.05).Logistic stepwise regression analysis revealed that renal dysfunction was the independent influential factor for prognosis.Conclusion Renal dysfunction is an important risk factor related to prognosis for critical newborn with cardiac conduction block.