沙眼衣原体和解脲支原体与不育不孕症的相关性研究

目的:探讨沙眼衣原体(chlamydia trachomatis,CT)和解脲支原体(ureaplasma urealyticum,UU)引起的泌尿生殖道感染与女性不孕症的关系。方法:检测112例不孕症患者,宫颈黏液的CT(免疫荧光法)和UU(液体培养法),于检查后1个月～6个月内月经后3 d～7 d行子宫输卵管碘油造影或腹腔镜检查,了解输卵管通畅情况。同时对100例有正常生育史的女性进行CT和UU检测。结果:不孕妇女CT和UU阳性检出率分别为62例(55.4%)和82例(71.4%),对照组分别为28例(28.0%)和22例(22.0%),不孕不育妇女CT和UU阳性检出率显高于对照组妇女(P<0.01)。结论:生育期女性在排除其他非感染性因素基础上发生的不孕症与CT和UU感染有密切的病因学关系。

The Association of Chlamydia Trachomatis and Ureaplasma Urealyticum Infection in Infertility

Objective To study the relationship between the infection of chlamydia trachomatis (CT) and ureaplasma urea- lyticum(UU)and tubal infertility.Methods CT was detected by immunofluorescence and UU detected by liquid incubation in the secretions of uterine cervix of women who suffered from primary infertility and secondary infertility.The appearance of fallo- pian tubes was examined by celoscope and tubography in 1 to 6 months after pathogen detection.Results The positively infec- ted rate of CT and UU is respectively 62(55.4% ) and 80(71.4%),the control is 28(28.0%) and 22(22.0%).It was prominenced discrepancy between patient and normal volunteers(P<0.01).Conclusion The infertile women in child-bearing period without suffering from other infectious agents are closely correlated with CT and UU.