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流行性出血热患者可溶性白细胞介素-2受体的动态观察
引用本文:徐新献,胡国斌,严宗琳,张艳秋,罗端德,张建傲,曾令兰,袁学文.流行性出血热患者可溶性白细胞介素-2受体的动态观察[J].咸宁医学院学报,1995,9(1):24-26.
作者姓名:徐新献  胡国斌  严宗琳  张艳秋  罗端德  张建傲  曾令兰  袁学文
作者单位:[1]通城县实习医院传染科 [2]同济医科大学协和医院传染科 [3]咸宁医学院附属医院传染科
摘    要:应用双抗体夹心ELISA法检测了20例流行性出血热(EHF)患者外周血清可深性白细胞介素-2受体(SIL-2R)浓度的动态变化。结果表明EHF患者SIL-2R浓度在发热期、低血压期、少尿期及多尿期均显著高于健康对照组,并且随病情加重而明显升高。研究提示SIL-2R升高与EHF免疫病理损伤相关,动态检测SIL-2R对判定患者病情变化有一定意义。

关 键 词:患者  SIL-2R  EHF  流行性出血热  可溶性白细胞介素-2受体  动态观察  升高  判定

The Dynamic Observation of Soluble Inteleukin-2 Receptor in Patients with Epidemic Hemorrhagic Fever
Xu Xinxian et al.The Dynamic Observation of Soluble Inteleukin-2 Receptor in Patients with Epidemic Hemorrhagic Fever[J].Journal of Xianning Medical College,1995,9(1):24-26.
Authors:Xu Xinxian
Institution:Xu Xinxian et al Department of Infectious Diseases,Tongcheng Cornty Peoples Hospital
Abstract:The level of soluble interleukin-2 receptor (SIL-2R) was measured dynamically in serum samples from 20 patients with epidenmic hemorrhagic fever (EHF) by double antibody sandwich ELBA method. The result indicated that the SIL-2R level in febrile, hypotensive, oliguric and multiuric phase of the patients with EHF is signifcantly higher than that of healthy control group and it is increased signifcantly with aggravation of state of an illness. It suggested that the increase of SIL-2R being related to the immunopathological injury with EHF. Dynamic meaasurement of SIL-2R may be valuable in determining the changes of the diseases.
Keywords:epidemic hemorrhagic fever  soluble interleukin-2 recetor
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