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血清总胆汁酸测定在慢性肝炎与肝炎后肝硬化的临床意义
引用本文:陈洁,何健军,屠士行.血清总胆汁酸测定在慢性肝炎与肝炎后肝硬化的临床意义[J].浙江预防医学,2002,14(3):13-14.
作者姓名:陈洁  何健军  屠士行
作者单位:杭州市第六人民医院,浙江,杭州,310014
摘    要:目的 探讨慢性肝炎、肝炎后肝硬化患者血清总胆汁酸 (TBA)的临床意义。方法 经肝穿活检病理证实为慢性肝炎、肝炎后肝硬化者 ,测定其TBA ,并与ALT、Tbil进行对比分析。结果 慢性肝炎、肝炎后肝硬化TBA与正常组比较有显著性差异。结论 慢性肝炎、肝炎后肝硬化时TBA检测与ALT、Tbil同样具有高度的敏感性 ,并可判断病情的预后。

关 键 词:慢性肝炎  肝炎后肝硬化  总胆汁酸  谷丙转氨酶  总胆红素
文章编号:1007-0931(2002)03-0013-02
修稿时间:2001年6月28日

The clinical significance of determination for the serum total bile acid in chronic hepatitis and post-hepatitic cirrhosis
Chen Jie,He Jianjun,Tu Shihang.The clinical significance of determination for the serum total bile acid in chronic hepatitis and post-hepatitic cirrhosis[J].Zhejiang Journal of Preventive Medicine,2002,14(3):13-14.
Authors:Chen Jie  He Jianjun  Tu Shihang
Affiliation:Chen Jie,He Jianjun,Tu Shihang. The Sixth City Hospital of Hangzhou,Zhejiang,310014 P. R. China.
Abstract:Objective To understand the clinical significance of determining the serum total bile acid (TBA) in chronic hepatitis and post-hepatitic cirrhosis. Methods All patients were biopsied to prove chronic hepatitis (82 cases) and post-hepatitic cirrhosis (24 cases). TBA was tested and contrasted to ALT and total bilirubin (Tbil). Results There was a significant difference between the groups of chronic hepatitis, post-hepatitic cirrhosis and the normal control group. Conclusions The determination of TBA has the similar sensitivity as ALT and Tbil in chronic hepatitis and post-hepatitic cirrhosis, and it may predict the prognosis.
Keywords:Chronic hepatitis    Posthepatitic cirrhosis    Total bile acid    ALT    Tbil
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