脊髓亚急性联合变性磁共振诊断价值

目的:评价MRI对恶急性联合变性(SCD)的诊断价值。方法:搜集21例临床怀疑SCD的患者行MRI矢状面T1 WI和T2WI、横轴面T2WI,其中8例行Gd DTPA增强扫描,10例治疗后行MRI复查。结果:所有患者均显示 T2WI上颈髓、胸髓后部、侧索呈高信号,有1例前索出现类似病灶,Gd-DTPA增强扫描所有病变区均未见明显强化。10 例经维生素B12治疗6-12个月后复查,示T2WI上原高信号病灶范围明显缩小或消失,与患者临床症状和体征的缓解和改善呈正相关。结论:MRI有助于SCD的诊断并可观察临床疗效。

MRI Diagnosis of Subacute Combined Degeneration of the Spinal Cord

Objective:To study the magnetic resonance imaging (MRI) manifestations in patients with subacute combined degeneration(SCD) of the spinal cord and its value for diagnosis was evaluated. Methods: 21 patients who were clinically suspected to have SCD underwent cervical and/or thoracic spinal MRI study, including sagittal T1WI and T2WI and axial T2-weighted sequences. Eight of the patients had iv gadopentetate dimeglumine(Gd-DTPA) administration for enhancement. Results: All patients had increased T2-weighted signal intensity in the dorsal and/or lateral columns of the cervical and/or thoracic spinal cord. No evidence of enhancement after Gd-DTPA administration. In 10 patients who had improved clinical symptoms after vitamin B12 treatment demonstrated definitely reduction or disappearance of the high signal intensity lesion in the spinal cord on T2WI in the follow-up MRI at 6 to 12 months respectively. Conclusion:MRI is helpful in the diagnosis and treatment surveillance of SCD.