| 骨基质明胶(同种异体)复合释放系统的抗原性研究 |
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| 引用本文： | 刘新,宫琳,徐勇忠. 骨基质明胶(同种异体)复合释放系统的抗原性研究[J]. 口腔医学研究, 1997, 0(4) |
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| 作者姓名： | 刘新 宫琳 徐勇忠 |
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| 作者单位： | 白求恩医科大学口腔医学院口腔颌面外科!长春130041 |
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| 摘 要： | 本研究旨在探讨骨基质明胶（BMG）复合释放系统（DS）在骨修复过程的的抗原性。在40只Wistar大白鼠的下颌骨缺损处植入BMG＋DS复合材料，通过术后3天、7天、14天及1月观察，抽取外周血，采用淋巴细胞转化试验和IL－2测定方法进行检测，结果表明P＞0．05，无显著性差异，说明BMG＋DS复合材料移植无抗原性，宿主不对其发生免疫排斥反应。
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| 关 键 词： | 骨基质明胶 释放系统 抗原性 |
Study on the Antigenicity of Compound Bone Matrix Gelatin and Delivery system |
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| Liu Xin,Gong Lin, Xu Yongzhong,. Study on the Antigenicity of Compound Bone Matrix Gelatin and Delivery system[J]. Journal of Oral Science Research, 1997, 0(4) |
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| Authors: | Liu Xin Gong Lin Xu Yongzhong |
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| Abstract: | In order to study the antigenicity of bone rnatrix gelatin (BMG) and delivery sysiem (DS) in bone repairingprocedure, we used forty Wistar rats in our experiment. The material was transplanted on the rat's mandibular defect. After 3, 7, 14, 30 days the external blood was extractecl. We detected the antigenicity by usinglymphocyte blastogenesis test and the measurement of IL - 2. The results showed that there was no difference between the experimental and the contral groups (P >0.05). It was suggested that the conipositetransplanting of BMG and DS have no immunogenicity and no immunology repelling reaction to body. |
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| Keywords: | bone matrix gelatin delivery system antigenicity |
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