骨缺损修复材料可降解速固化骨水泥结构特征及力学性能

目的分析异体脱钙骨基质(DBM)骨粒复合磷酸钙骨水泥(CPC)及氰基丙烯酸正丁酯粘合剂(NBCA)后材料的扫描电镜结构特征及生物力学性能。方法将DBM骨粒与CPC以1:1体积比搅拌均匀,加入适量NBCA,制成DCN骨水泥;扫描电镜观察复合材料结构特征,力学试验机测定材料生物力学性能。结果扫描电镜发现,CPC与DBM均匀复合,CPC被覆DBM表面呈规则有序海绵状,其中存在较多大小不规则、相互连通的自然裂隙;材料的抗压及拉伸极限强度较CPC明显提高。结论DCN骨水泥具有相互联通的自然裂隙及潜在的骨粒通道,并可提供较好的机械支持和固定作用的骨修复材料。

Constructive and biomechanical properties of the newly prepared bone cement

Objective To analyze constructive and biomechenical properties of material impregnated decalcified bone matrix (DBM) with calcium phosphate cement(CPC)and N butyl cyanoacrylate(NBCA).Methods The DBM particles were made and the materials impregnated 1:1 volume mass ratio DBM particles with CPC, addin NBCA, made DCN cement.The compound material constructions were observed by scanning electron microscope(SEM) and their biomechenical properties were measured by mechenics testing machine.Results The DBM particles and CPC were even mixed with irregular gaps existing within interspace and connected by the multipolar mode in DCN cement;DCN cement have a darity outline and compact structure, CPC covered DBM surface with regular sponge constructure.Compared with CPC,The ultimate compressive strengths and pull extend strengths of DCN cement were markedly increased than CPC.Conclusions DCN cement had much more irregular gaps existing within interspace.The materials may be a new type of bone cement which could provide abundant biomechenical support.