| 瘦素对肝纤维化作用机制的研究 |
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| 引用本文： | 王丽婷,马红,贾继东. 瘦素对肝纤维化作用机制的研究[J]. 基础医学与临床, 2006, 26(1): 42-45 |
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| 作者姓名： | 王丽婷 马红 贾继东 |
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| 作者单位： | 首都医科大学,北京友谊医院肝病研究中心,北京,100050 |
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| 摘 要： | 瘦素和肝纤维化的关系越来越引起人们的关注,瘦素和它的功能性受体在肝纤维化的形成中起着重要的作用。然而,其具体作用机制不明,目前存在两种不同观点。免疫系统和有关的细胞因子也参与了瘦素的作用。探求瘦素的作用机制以期为肝纤维化的治疗提供新的途径。
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| 关 键 词： | 瘦素 肝纤维化 |
| 文章编号： | 1001-6325(2006)01-0042-04 |
| 收稿时间： | 2005-03-14 |
| 修稿时间： | 2005-03-29 |
Effects of leptin on hepatic fibrosis |
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| WANG Li-ting,MA Hong,JIA Ji-dong. Effects of leptin on hepatic fibrosis[J]. Basic Medical Sciences and Clinics, 2006, 26(1): 42-45 |
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| Authors: | WANG Li-ting MA Hong JIA Ji-dong |
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| Affiliation: | Liver Research Center, Beijing Friendship Hospital, Capital University of Medical Science, Beijing 100050, China |
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| Abstract: | Leptin and its functional receptors play a crucial role in hepatic fibrogenesis.However,the precise mechanisms underlying the profibrogenic action of leptin in the liver has not been well elucidated.There are two different mechanisms at present.Immunity system and some cytokines may act on it.The reseach on the mechanism of leptin offer a new way for the clinical treatment of hepatic fibrosis. |
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| Keywords: | leptin hepatic fibrosis |
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