我院围手术期抗菌药物预防性应用调查分析

目的：调查我院围手术期预防性应用抗菌药物的情况。方法：回顾性分析我院2011年7月-12月104例住院患者的病历资料，评价围手术期抗茵药物预防应用的合理性。结果：抗菌药物的不合理应用病例占56．73％；使用的抗菌药物以头孢菌素类为主；单一用药率92．30％，二联用药率7．70％，无三联及以上联合用药；不合理用药主要表现在术后用药时间长、给药时机不当、选药档次高、用法用量不当等。结论：我院围手术期抗茵药物应用存在明显不合理现象，医院应采取积极措施，加强抗菌药物的培训管理，规范围手术期抗菌药物的使用。

A Survey and Analysis of the Preventive Application of Antibacterials during Perioperative Period in Our Hospital

Objective： To investigate the preventative application of antibacterials during perioperative period in our hospital. Methods： A retrospective investigation was conducted to analyze the clinical data of the inpatients from Jul. to Dec. of 2011 in our hospital and to evaluate the rationality of the use of antibacterials during perioperation. Results： The rate of irrational use of antibacterials during perioperation was 56.73%. Cephalosporins were used with the highest frequency. The rate of single agent use was 92.30% and that of combined use of two antibacterials was 7.70%. There was no case of combined use of three or more than three antibacterials. The irrational drug use was mainly manifested in the postoperative long medication, improper timing of administration, high grade drug selection and in- appropriate usage or dosage, etc. Conclusion： Irrational use of antibacterials during perioperation existed in our hospi- tal, therefore measures need to be taken by the hospital to improve the training on the correct use of antibacterials and to strengthen the management on the preventative application of antibacterials during perioperative period.