Malignant melanoma of the anorectum: report of four cases |
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| Authors: | Fukui Rika Hata Fumitake Yasoshima Takahiro Honma Toshio Nomura Hiroki Sasaki Kenichi Nishimori Hidefumi Sasaki Kazunori Kutomi Goro Ohno Keisuke Oikawa Ikuo Sasaki Kazuaki Tarumi Ken Ishiyama Yuuji Kobayashi Kenji Yamamoto Naoya Hirata Koichi |
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| Institution: | (1) First Department of Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan, JP;(2) Department of Surgery, Sapporo Ishiyama Hospital, South-15, West-11, Chuo-ku, Sapporo 0604-0915, Japan, JP;(3) Department of Surgery, Sapporo General Hospital of Hokkaido Railway Company, North-3, East-1, Chuo-ku, Sapporo 060-0033, Japan, JP;(4) Department of Surgery, Sapporo Geka-Kinen Hospital, South-23, West-15, Chuo-ku, Sapporo 064-0923, Japan, JP |
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| Abstract: | Four cases of anorectal malignant melanoma are reported in this paper. All patients underwent an abdominoperineal resection
with lymph node dissection for a curative operation and received postoperative chemotherapy with dacarbazine, ranimustine,
and vincristine, either with or without interferon-β. One of these patients has been observed for more than 6 years postoperatively
without any evidence of recurrence. The other three patients had advanced diseases at the time of diagnosis, and died within
3 years after operation. The prognosis of anorectal malignant melanoma is considered to be directly related to tumor size
and depth. Therefore, a staging system and treatments based on the tumor size and depth (or thickness) are needed.
Received: March 28, 2001 / Accepted: November 20, 2001 |
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| Keywords: | Malignant melanoma Anorectal neoplasm Mucosal melanoma |
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