放射性核素显像对伴心脏损害的风湿病的检测意义

目的　探讨某些活动期风湿病患者左心室功能改变、心肌损害以及放射性核素显像检测风湿病患者心脏损害的临床应用价值。方法　用放射性核素显像平衡法门电路心血池扫描及心肌断层显像测定２０ 例正常人和２０ 例系统性红斑狼疮（ＳＬＥ） ，６ 例多发性肌炎（ＰＭ），６ 例结节性动脉炎（ＰＡＮ），５ 例风湿热患者左心室收缩和舒张功能改变、心肌损害情况。结果　活动期风湿病病人的左室射血分数（ＬＶＥＦ），高峰射血率（ＰＥＲ），高峰充盈率（ＰＦＲ） ，左室相角程（ＳＨ） 均较正常对照有显著差异（ Ｐ＜ ０－０１） ，室壁活动异常的阳性率为４８－６ ％ ，心肌显像阳性率为５７－７ ％ 。结论　活动期风湿病患者左心室功能及心肌明显损害，放射性核素显像可客观评价风湿病患者心脏损害，对临床治疗有指导意义。

Evaluation of left ventricular function in rheumatic disease using radionuclide ventriculography

Objective To evaluate the left ventricular function of rheumatic disease by equilibrium radionuclide ventriculography.Methods Twenty normal controls and 37 patients with rheumatic disease were studied by gated cardiae blood pool imaging and gated myocardial imaging,and the left ventricular systolic and diastolic parameters were analysed.Results The parameters of systolic and diastolic function were lower in patients than those in controls ( P <0 01).Conclusion Radionuclide ventriculography is useful to evaluate the cardiae function in rheumatic disease and also helpful for the treatment and prognosis of the disease.