降气消瘀汤治疗老年高血压脑出血微创术后临床研究

目的:观察降气消瘀汤对老年高血压脑出血(HCH)微创术后的恢复效果。方法:将老年HCH微创手术患者64例,按随机数字表法分为观察组与对照组各32例。对照组采用常规治疗,观察组在对照组的基础上联合降气消瘀汤治疗。2组均以2周为1个疗程,共治疗2个疗程。观察2组临床疗效及治疗前后脑出血量情况,比较2组治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、生活质量评分量表(ADL)评分变化,以及血清白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)水平变化。结果:观察组总有效率为93.75%,对照组为71.88%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组脑出血量显著低于治疗前(P<0.05),且观察组脑出血量明显低于对照组(P<0.05)。治疗后,2组ADL评分均高于治疗前(P<0.05),且观察组ADL评分显著高于对照组(P<0.05)。治疗后,2组IL-6、IL-8、TNF-α水平均低于治疗前(P<0.05),且观察组各项指标均低于对照组(P<0.05)。结论:降气消瘀汤治疗能显著提高老年HCH患者术后的临床效果,改善脑出血量,有效促进神经组织修复,降低血清炎症因子水平,提高患者生活质量。

Clinical Study on Jiangqi Xiaoyu Tang for Senile Patients with Hypertensive Cerebral Hemorrhage After Minimally Invasive Surgery

Objective:To observe the recovery effect of Jiangqi Xiaoyu tang for senile patients with hypertensive cerebral hemorrhage(HCH)after minimally invasive surgery.Methods:A total of 64 cases of senile patients with HCH undergoing minimally invasive surgery were divided into the observation group and the control group according to the random number table method,32 cases in each group.The control group was given routine treatment,and the observation group was additionally treated with Jiangqi Xiaoyu tang based on the treatment of the control group.Both groups were treated for two courses,two weeks being a course.The clinical effect and the amount of cerebral hemorrhage before and after treatment were observed in the two groups.Before and after treatment,the changes in score of National Institutes of Health Stroke Scale(NIHSS)and Activity of Daily Living(ADL)were compared between the two groups;the changes in levels of interleukin-6(IL-6),interleukin-8(IL-8),and tumor necrosis factor-α(TNF-α)in serum were compared between the two groups.Results:The total effective rate was 93.75%in the observation group,and 71.88%in the control group,the difference being significant(P<0.05).After treatment,the amount of cerebral hemorrhage in the two groups was significantly lower than that before treatment(P<0.05),and the amount in the observation group was significantly lower than that in the control group(P<0.05).After treatment,the ADL scores in the two groups were higher than those before treatment(P<0.05),and the score in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the levels of IL-6,IL-8 and TNF-αin the two groups were lower than those before treatment(P<0.05),and the indexes above in the observation group were lower than those in the control group(P<0.05).Conclusion:In the treatment of senile HCH patients,the therapy of Jiangqi Xiaoyu tang can significantly enhance the clinical effect,reduce the amount of cerebral hemorrhage,effectively promote the repair of nervous tissue,reduce levels of inflammatory factors in serum,and improve quality of life.