首页 | 本学科首页   官方微博 | 高级检索  
检索        

利培酮对阴性精神分裂症认知损害的影响研究
引用本文:龙彬,蒋良函,易正辉,钱竹书,朱丽萍.利培酮对阴性精神分裂症认知损害的影响研究[J].中国现代临床医学,2006,5(10):23-25.
作者姓名:龙彬  蒋良函  易正辉  钱竹书  朱丽萍
作者单位:上海交通大学医学院附属精神卫生中心,201108
摘    要:目的 了解利培酮治疗对阴性精神分裂症病人认知功能的影响及阴性症状改善与认知功能的关系。方法 对阴性精神分裂症患者利培酮治疗前后进行阴性症状评定量表(SANS)、简明精神病评定量表(BPRS)评定精神症状;用Wisconsin卡片分类测验(WCST),Wechsler记忆测验(WMS)、Wechsler成人智力量表(WAIS-RC)评定认知功能。结果 利培酮组能改善精神症状、记忆、执行功能,SANS因子分的减分与WMS中理解、背数量表分和WCST分的进步相关。结论 利培酮对阴性精神分裂症病人的精神症状和部分认知损害有改善,阴性症状的改善与认知功能的提高有明显相关性。

关 键 词:利培酮  阴性分裂症  精神症状  认知损害
文章编号:1726-8648(2006)10-0023-03
收稿时间:2006-07-21

A Study of Risperidone on Improvement of Cognitive Impairment in Negative Schizophrenia
Long Bin, Jiang Lianghan, Yi Zhenghui,et al..A Study of Risperidone on Improvement of Cognitive Impairment in Negative Schizophrenia[J].Chinese Journal of Clinical Medicine,2006,5(10):23-25.
Authors:Long Bin  Jiang Lianghan  Yi Zhenghui  
Institution:Long Bin, Jiang Lianghan, Yi Zhenghui, et al.
Abstract:Objective To explore the effect of risperidone on cognitive impairment in negative schizophrenia and the relationship of improvement of psychotic symptoms and cognitive impairment. Methods Negative symptoms, memory, attention, executive function were assessed with BPRS, SANS, WMS, WAIS-RC and WCST before and after treatment in patients taking risperidone. Results Risperidone can significantly improve psychotic symptoms, memory and executive function. There were a positive correlation between the descending of SANS factors scale and improvement of WMS and WCST. Conclusion Risperidone can improve the negative symptoms and part cognitive impairment of negative schizophrenia. The improvement of psychotic symptoms has marked correlation with enhancement of cognitive function.
Keywords:Risperidone Negative schizophrenia Psychotic symptoms Cognitive impairment
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号