Effects of low-power laser irradiation on survival of random skin flap in rats |
| |
| Authors: | Email author" target="_blank">M?BayatEmail author M?R?Tabatabai H?Shemshadi |
| |
| Institution: | (1) Department of Anatomy and Cell and Molecular Biology Research Center, Medical Faculty, Shaheed Beheshti University of Medical Sciences, PO Box 19395/4719, Evin, Tehran, Iran;(2) Hospital of National Iranian Company of Oil, Ahvaz, Iran;(3) Department of Speech Therapy, University of Welfare and Rehabilitation Sciences, Tehran, Iran |
| |
| Abstract: | This research was designed to study the effects of low-power helium–neon (He–Ne) laser irradiation on random skin flap survival in rat. Fifty 50 male rats were randomly divided into five groups. On the dorsum of each rat, one full thickness random skin flap which contained no specific vessel was elevated. Groups 1 to 4 were exposed to different models of a low-power He–Ne laser. Group 5 rats received no laser treatment and were considered as the control group. The energy density of the He–Ne laser used was 0.2 J/cm2. Immediately after surgery and at day 7, the surface area of all flaps was determined. Histological and tensiometrical studies on the surviving part of the flaps were also performed. The data obtained were analyzed by ANOVA. The results showed a significant difference in the surface area of survival parts of flaps and density of blood vessels on day 7 between group 3 rats and the other groups (P=0.0188, P=0.0455). Low-power He–Ne laser irradiation of flaps without recognized blood vessels in rats, reduced vasospasm, produced vasodilation, and caused a significant increase in the surviving surface area.Presented at the 14th World Congress of the International Society for Laser Surgery and Medicine, India, 27–30th August, 2001 |
| |
| Keywords: | Random skin flaps Low-power laser Survival Tensile strength Histology Rat |
| 本文献已被 SpringerLink 等数据库收录！ |
|
