应用三维有限元分析正常站立位股骨近端结构生物力学特性

背景：目前股骨有限元研究较多，但以往的研究多集中于股骨外部的生物力学方面。目的：建立股骨近端结构三维有限元模型，对正常站立位下的股骨近端生物力学特性进行分析以指导临床工作。设计、时间及地点：三维有限元建模及力学分析，于2009-04在天津医科大学总医院骨科生物力学实验室完成实验。对象：天津医科大学总医院志愿者1名，男性，30岁，应用X射线排除股骨病变及损伤等情况。方法：在Mimics中直接读取符合Dicom 3.0 标准的股骨近端原始CT数据，经阈值设定、区域增长及形态学操作等生成股骨初始3D模型，后期结合有限元软件ANSYS生成最终的三维有限元网格模型，然后在ANSYS中分别对应用Mimics得到的模型加载200 N的垂直载荷, 观察股骨近端内部应力分布。主要观察指标：对模型施加200 N垂直载荷，观察股骨近端的Von mises应力分布。结果：应用Mimics和Ansys软件建立股骨近端有限元模型，观察到股骨近端内部应力分布，验证了结构与功能的对应关系。结论：应用Mimics可以建立更符合股骨近端机械结构和力学性质的三维有限元模型，据此模型得到的股骨近端力学特性分析结果更为可信，以辅助指导临床应用。关键词：股骨；有限元模型；生物力学

Application of three-dimensional finite element analysis in biomechanical properties of proximal femoral structure under the normal standing position

AbstractBACKGROUND:At present,there are many established femoral finite element study,but previous studies focused on femoral biomechanics of the outside.OBJECTIVE:To establish three-dimensional finite element model of structure of the proximal femur,and analyze its biomechanics in normal standing position to provide reasonable evidence for clinic application.DESIGN, TIME AND SETTING: Three-dimensional finite element models were created in the laboratory of Orthopaedic Biomechanics, Tianjin Medical University in June 2009.PARTICIPANTS:One volunteer was enrolled at Tianjin Medical University, male, 30 years old. Femur lesion or injury was excluded by means of X-ray.METHODS: The primitive femur CT data were adopted according to Dicom 3.0 standard in Mimics,obtain the primitive three-dimensional femur model was established in threshold defining,region enlarging and morphological performing.Remesh the primitive model and combined it with ANSYS software to create the final finite-element model. The model obtained by using the Mimics and the model were loaded with 200 N vertical loading in ANSYS respectively. Then checked out the difference of their stress distribution.MAIN OUTCOME MEASURES: Using 200 N as the external load in the vertical direction, the Vonmises stress distribution of the femur was detected.RESULTS:The applications of Mimics and Ansys software can create a finite element model of proximal femur.It was found that the correspondent relationship between stress and structure proximal femur in is verified as expected.CONCLUSION:Mimics can build applications more in line with the proximal femoral mechanical structure and mechanical properties of three-dimensional finite element model, which model the mechanical properties of the femur is more credible the results of the analysis to support the clinical application of the guidance.KEY WORDS:femur;finite element model;biomechanics