| 树突状细胞的补体攻膜复合物C5b-9模型的建立 |
| |
| 引用本文： | 吴佩泽,杨明会,杨雪梅. 树突状细胞的补体攻膜复合物C5b-9模型的建立[J]. 中国现代医药杂志, 2008, 10(3): 19-21 |
| |
| 作者姓名： | 吴佩泽 杨明会 杨雪梅 |
| |
| 作者单位： | 中国人民解放军总医院内科临床部,北京,100853 |
| |
| 摘 要： | 目的 建立树突状细胞(DC)的补体攻膜复合物C5b-9模型,为研究补体攻膜复合物对DC的影响奠定基础.方法 诱导人外周血单核细胞分化成为不成熟DC,C5b-9体外组装,激光共聚焦检测C5b-9在DC表面组装情况.结果 成功诱导出不成熟DC,激光共聚焦显示C5b-9完整组装于DC表面.结论 本研究成功建立了DC的补体攻膜复合物C5b-9模型,为将来进一步探讨C5b-9对DC的功能影响奠定了基础.
|
| 关 键 词： | DC 补体攻膜复合物C5b-9 激光共聚焦 树突状细胞 补体攻膜复合物 模型 model complex attack 功能影响 表面组装 显示 激光共聚焦 结果 情况 共聚焦检测 体外组装 细胞分化 单核 人外周血 方法 研究 |
| 修稿时间： | 2007-12-20 |
Establish the membrane attack complex C5b-9 model of DC |
| |
| Wu Peize,Yang Minghui,Yang Xuemei. Establish the membrane attack complex C5b-9 model of DC[J]. Modern Medicine Journal of China, 2008, 10(3): 19-21 |
| |
| Authors: | Wu Peize Yang Minghui Yang Xuemei |
| |
| Affiliation: | Wu Peize,Yang Minghui,Yang Xuemei. Department of Clinical Medicine,People's Liberation Army Hospital,Beijing 100853 |
| |
| Abstract: | Objective To establish the membrane attack complex C5b-9 model of DC. Methods DC was induced in vitro,C5b-9 was assembled on the surface,and the formation of C5b-9 on the membrane of DC was verified by laser scanning confocal microscopy. Results DC was induced successfully in vitro,and the membrane attack complex C5b-9 was assembled successfully. Conclusion The membrane attack complex C5b-9 model of DC was established successfully which might provide the foundation for functional study. |
| |
| Keywords: | DC C5b-9 Laser scanning confocal microscopy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
