| 18F-FDG PET/CT在查找骨转移瘤原发灶中的价值 |
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| 引用本文： | 梁颖,吴宁,李蒙,郑容,刘瑛,张雯杰,李静,赵平.18F-FDG PET/CT在查找骨转移瘤原发灶中的价值[J].中国医学影像技术,2009,25(12):2275-2278. |
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| 作者姓名： | 梁颖 吴宁 李蒙 郑容 刘瑛 张雯杰 李静 赵平 |
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| 作者单位： | 中国医学科学院,北京协和医学院,肿瘤医院PET/CT中心,北京,100022 |
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| 摘 要： | 目的 探讨~(18)F-FDG PET/CT在查找骨转移瘤原发灶中的应用价值及不同类型骨转移瘤的PET/CT特点.方法 回顾性分析34例原发灶不明的骨转移瘤患者病例资料,经常规检查未发现原发灶,行~(18)F-FDG PET/CT扫描查找原发灶.比较溶骨性转移瘤和成骨性转移瘤SUVmax的差异.结果 经组织细胞学或3个月以上的临床随访证实,34例患者中,PET/CT检出22例原发灶(64.71%).12例PET/CT未发现原发灶(35.29%).23例溶骨性为主转移瘤和11例成骨性为主转移瘤的SUV_(max)分别为6.78±3.66和4.13±1.69(P＜0.05).结论 ~(18)F-FDG PET/CT显像可提示多数骨转移瘤患者的原发灶,进而指导患者的治疗计划.溶骨性转移瘤的代谢活性较成骨性转移瘤更高.
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| 关 键 词： | 骨肿瘤 体层摄影术 发射型计算机 体层摄影术 X线计算机 ~(18)F氟脱氧葡萄糖 |
| 收稿时间： | 2009/2/11 0:00:00 |
| 修稿时间： | 2009/8/19 0:00:00 |
Value of 18F-FDG PET/CT in detecting primary tumor in patients with bone metastases |
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| LIANG Ying,WU Ning,LI Meng,ZHENG Rong,LIU Ying,ZHANG Wen-jie,LI Jing and ZHAO Ping.Value of 18F-FDG PET/CT in detecting primary tumor in patients with bone metastases[J].Chinese Journal of Medical Imaging Technology,2009,25(12):2275-2278. |
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| Authors: | LIANG Ying WU Ning LI Meng ZHENG Rong LIU Ying ZHANG Wen-jie LI Jing and ZHAO Ping |
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| Institution: | PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100022, China |
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| Abstract: | Objective To assess the value of ~(18)F-FDG PET/CT in detecting primary tumors of patients with bone metastases, and to observe PET/CT characteristics of different types of bone metastases. Methods Whole-body ~(18)F-FDG PET/CT images of 34 patients with metastatic bone from unknown primary tumor (CUP) were retrospectively analyzed, and SUVmax was compared in osteolytic and osteoblastic subgroups based on CT characteristics. Results Diagnosis of these patients were confirmed by histopathological findings or ≥3 months follow-up. Primary tumors were detected with PET/CT in 22 patients (64.71%). SUV_(max) was 6.78±3.66 in 23 osteolytic metastases, and 4.13±1.69 in 11 osteoblastic metastases (P＜0.05). Conclusion ~(18)F-FDG PET/CT is helpful to find the localization of unknown primary tumors in patients with bone metastases, and to make treatment Planning. Osteolytic metastases show higher metabolic activity on ~(18)F-FDG PET/CT. |
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| Keywords: | Bone neoplasms Tomography emission computed Tomography X-ray computed Fluorodeoxyglucose F18 |
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