| NPC与MPV方案治疗晚期非小细胞肺癌的疗效比较 |
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| 引用本文： | 刘健,魏于全,陈兆红.NPC与MPV方案治疗晚期非小细胞肺癌的疗效比较[J].华西医学,2003,18(1):9-10. |
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| 作者姓名： | 刘健 魏于全 陈兆红 |
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| 作者单位： | 1. 四川大学华西医院教育部人类疾病生物治疗重点实验室与肿瘤中心,四川成都,610041
2. 德阳市人民医院肿瘤科 |
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| 摘 要： | 目的：比较NPC与MPV方案治疗晚期非小细胞肺癌（NSCLC）的疗效。方法：64例晚期NSCLC患者采用NPC32例，采用Kaplan-Meier方法分析患者生存期。采用Cox比例风险模型分析影响预后的因素。结果：MPV组中位生存期为8个月，NPC组中位生存期12个月。两组生存期差异有显著性（P＜0．005，0．001）化疗的毒副反应主要是胃肠道反应和骨髓抑制。结论：NPC比MPV能延长患者生存期，但并没有增加毒副反应。
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| 关 键 词： | 非小细胞肺癌 药物治疗 NPC方案 MPV方案 预后 |
| 文章编号： | 1002-0179(2003)01-0009-02 |
Retrospective Comparison between NCP and MPV Protocls for Advanced Non-small Cell Lung Cancer |
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| LIU Jian,WEI Yu-quan,CHEN Zhao-hong.Retrospective Comparison between NCP and MPV Protocls for Advanced Non-small Cell Lung Cancer[J].West China Medical Journal,2003,18(1):9-10. |
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| Authors: | LIU Jian WEI Yu-quan CHEN Zhao-hong |
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| Abstract: | Objective:To compare the theapeutic effects between NCP and MPV protocols for advanced non-small cell lung cancer(NSCLC).Methods:Sixty-four patieuts havin advanced non-small cell lung cancer,the NPC and MPV Kaplan Meier meehods,were adopted to studdy 32 patients in eachs respectively for the survival rate and the cox regression prognostic factors.Results:The overall median two-years survival time in the MPV group was 8 months,and 12 months in the NPC group.The major toxic effects of the two groups were gastrointerstinal tract reactions and myelosuppression.Conclusion:NPC chemotherapy can prolong the survival time more in patients with advanced NSCLC than MPV chemotherapy but without increasing its toxicity. |
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| Keywords: | Lung neoplasms/drug therapy Carcimoma non-small cell/drug therapy NPC protocol MPV protocots Prognosis |
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