疏风止嗽汤治疗慢性咳嗽的临床疗效

目的 探讨疏风止嗽汤治疗慢性咳嗽的临床疗效。 方法 选择2020年1—12月在乌兰察布市中医蒙医医院治疗的慢性咳嗽患者60例为研究对象，随机分为观察组与对照组，每组各30例。观察组采用疏风止嗽汤治疗，对照组采用孟鲁司特钠联合右美沙芬愈创甘油醚糖浆治疗。比较两组治疗前后中医证候积分、LCQ-MC评分，比较两组临床疗效、不良反应及复发率。 结果 治疗后两组中医证候积分均较治疗前显著下降，差异有统计学意义(P＜0.001)；治疗后观察组中医证候积分显著低于对照组，差异有统计学意义(P＜0.001)。观察组总有效率为93.3%，对照组总有效率为83.3%，差异无统计学意义(P＞0.05)；但观察组痊愈、显效率更高，秩和检验结果显示，差异有统计学意义(P＜0.05)。治疗后两组LCQ-MC评分均显著较治疗前升高，差异有统计学意义(P＜0.001)；治疗后，观察组LCQ-MC评分显著高于对照组，差异有统计学意义(P＜0.001)。观察组不良反应总发生率低于对照组，差异有统计学意义(P＜0.05)；观察组无复发情况，对照组有4例复发，差异有统计学意义(P＜0.05)。 结论 疏风止嗽汤治疗慢性咳嗽具有较好的临床疗效，并且不良发应少，复发率低，可显著改善患者的生活质量。

Clinical effect of Shufeng Zhisou Decoction on chronic cough

Objective To investigate the clinical effect of Shufeng Zhisou Decoction on chronic cough. Methods A total of 60 patients with chronic cough who were treated in Wulanchabu Hospital of Traditional Chinese Medicine and Mongolian Medicine from January to December 2020 were selected as the research objects and randomly divided into the observation group and the control group, with 30 patients in each group. The observation group was treated with Shufeng Zhisou Decoction, while the control group was treated with Montelukast sodium combined with dextromethorphan gualfenether syrup. The TCM syndrome score and LCQ-MC score before and after treatment were compared between the two groups, and the clinical efficacy, adverse reactions and recurrence rates of the two groups were compared. Results After treatment, TCM syndrome scores in both groups were significantly decreased compared with before treatment, with statistically significant differences (P<0.001). After treatment, the TCM syndrome score of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P<0.001). The total effective rate was 93.3% in the observation group and 83.3% in the control group, and no significant difference was observed between the two groups (P>0.05). However, higher recovery and significant efficiency were observed in the observation group, and the rank-sum test showed statistically significant difference between the two groups (P<0.05). After treatment, LCQ-MC in both groups were increased significantly compared with before treatment, with statistically significant differences (P<0.001). After treatment, the LCQ-MC score of the observation group was significantly higher than that of the control group, the difference was statistically significant (P<0.001). The total incidence of adverse reactions of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P<0.05). No recurrence was observed in the observation group and 4 patients with recurrence were observed in the control group, and the difference in the recurrence rate between the two groups was statistically significant (P<0.05). Conclusion Shufeng Zhisou Decoction has good clinical efficacy in treating chronic cough, with the fewer adverse reactions and low recurrence rate, which can significantly improve the quality of life of patients.