阴道镜辅助下LEEP刀手术治疗宫颈癌前病变的临床效果

目的 探讨阴道镜辅助下宫颈电热圈环形切除术(LEEP)治疗宫颈癌前病变的临床效果。 方法 选取滨州市妇幼保健院妇产科2018年10月至2019年12月收治的宫颈癌前病变患者82例,依据患者的治疗方案分组,每组各41例。其中对照组采用常规外科手术治疗,观察组在阴道镜下行LEEP切除治疗,比较两组患者手术基本情况、治疗疗效及术后随访情况。 结果 观察组手术时间、住院时间短于对照组,术中出血量少于对照组,差异有统计学意义(P＜0.001)。观察组治疗总有效率为97.56%(40/41),对照组治疗总有效率为82.93%(34/41),差异有统计学意义(P＜0.05)。随访显示观察组复发率与对照组比较,差异无统计学意义(P>0.05)。观察组术后并发症发生率低于对照组,差异有统计学意义(P＜0.05)。 结论 阴道镜下行LEEP刀治疗宫颈癌前病变,具有手术创伤小,术后恢复快的优势,同时安全性高,可有效降低术后复发及并发症发生,有较好的应用前景。

Clinical effect of colposcopy-assisted LEEP procedure in the treatment of cervical precancerous lesions

Objective To investigate the clinical effect of colposcopy-assisted loop electrosurgical excision procedure (LEEP) in the treatment of cervical precancerous lesions. Methods A total of 82 patients with cervical precancerous lesions admitted to the department of obstetrics and gynecology of Binzhou Maternal and Child Health Care Hospital from October 2018 to December 2019 were selected and grouped according to the treatment plan of the patients, with 41 cases in each group. The control group was treated with conventional surgery, and the observation group was treated with colposcopy-assisted LEEP resection. The basic conditions of the surgery, therapeutic effects and postoperative follow-up were compared between the two groups. Results The indictors including operation time and length of stay in the observation group was shorter than that in the control group, and the amount of intraoperative blood loss was less than that in the control group, with statistically significant differences (P<0.001). The total effective rate of treatment in the observation group was 97.56% (40/41), the total effective rate of treatment in the control group was 82.93% (34/41), and the difference was statistically significant (P<0.05). According to the follow-up data, there was no significant difference in terms of recurrence rate in the observation group and the control group (P>0.05). The incidence of postoperative complications in the observation group was lower than that in the control group, with statistically significant difference (P<0.05). Conclusion The colposcopy-assisted LEEP procedure for the treatment of cervical precancerous lesions shows the advantages of less surgical trauma and quick postoperative recovery and is of high safety. It can effectively reduce the incidences of postoperative recurrence and complications, and has a good application prospect.